Dedicated to Advancing Healthcare
Through Clinical Research

Since 1994, the Medical Center for Clinical Research (MCCR) has clinically tested and evaluated both new and previously approved medical treatments. With its roots in women's health, MCCR has studied treatments developed for a wide variety of women's health indications as well as numerous treatments for conditions affecting both men and women, such as irritable bowel syndrome (IBS), acne, migraine, overactive bladder, and benign prostatic hypertrophy (BPH). Director William D. Koltun MD, a board-certified obstetrician-gynecologist, has specialized in the treatment of menopause, osteoporosis, contraception, endometriosis, human papilloma virus (HPV), and female urology and has published extensively in his field. Dr. Koltun leads a well-trained medical staff, including a research site manager, a nurse midwife, study coordinators, and laboratory personnel specially trained in phlebotomy and other technical procedures required for clinical trials. All have expertise in the specific areas each study requires, ensuring a professional and successful experience.

Medical Center for Clinical Research is now a part of the Wake Research Organization of Unified Investigational Sites. Read more about our partner sites and global reach at

Please note that this Web site does not provide specific medical advice and does not replace medical consultation with a qualified healthcare professional. Participating in a clinical research study is a voluntary choice that may provide you with greater knowledge and understanding of your particular medical condition or disease. After completing an approved consent, you will have ample opportunity to discuss your medical condition with a compassionate healthcare professional. All questions regarding your proposed treatment, laboratory evaluations, and study medication will be addressed. No study procedures will be administered until you feel completely informed about all aspects of the study, including potential medication side effects and any interactions with other medications you may currently be taking and how much time will be required of you both in our office and at home. Compensation for your time and travel will be arranged at each office visit.

Still not sure if participating in a clinical trial is right for you? Our job at MCCR is to guide you through each step of the process, guaranteeing your safety and providing a rewarding experience.

  • What is the purpose of the study?
  • Who is going to be in the study?
  • How might this trial affect my daily life?
  • How long will the trial last?
  • Will hospitalization be required?
  • Will I be reimbursed for other expenses?
  • Who will be in charge of my care?
Contact Us About
A Clinical Trial
Plan ahead and write down possible questions to ask.
Ask a friend or relative to come along for support and to hear the responses to the questions.
Every clinical trial in the U.S. must be approved and monitored by an Institutional Review Board (IRB) to make sure the risks are as low as possible and are worth any potential benefits.